1. Understand your champion's playstyle: Each champion has a unique playstyle that requires specific runes to maximize their potential. For example, if you're playing a tanky champion like Maokai, you might want to choose defensive runes like Grasp of the Undying or Aftershock.

2. Consider your role: Different roles require different types of runes. For example, if you're playing as a support, you might want to choose utility-based runes like Summon Aery or Guardian.

3. Look at the current meta: The meta is constantly changing in League of Legends, and certain runes may be more effective than others depending on the current state of the game. Keep an eye on what other players are using and adjust accordingly.

4. Experiment: Don't be afraid to try out different rune combinations and see what works best for you and your playstyle.

5. Use online resources: There are many websites and guides available that can help you choose the best runes for your champion and role. Use these resources to your advantage and learn from experienced players.

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